The numberof milliosmols (mOsm) in a kilogram (kg)of solution.In humans normally the osmolality inplasma is about 275-295 mOsm/Kg 15. The following points highlight the two types of fluids in human body. The largest fluid ‘compartment’ which accounts for two-thirds (30L) of TBW is within the cells of the body and Fluid Concentration in Human Body: 1. Chart and Diagram Slides for PowerPoint - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. Bioelectrical impedance analysis (BIA) is a technique that has proven to be safe, generally acceptable to patients, and easy to use [109,110].BIA is used for determining fluid management and increasingly for evaluating protein-energy status. If we add an IV fluid and change the blood concentration that can effect water movement between plasma and the inside of red blood cells. body fluid compartments thursday, december 10, 2015 6. distribution of total bodyy water compartments volume (l) percentage body weight body water total body water 42 60 100 icf 28 40 67 ecf 14 20 33 plasma (25%) 3.5 5 8 interstitial fluid, transcellular fluid, mesenchymal tissue (75%) 10.5 15 25 thursday, december 10, 2015 7. Thomas Fuller Learning Outcomes 1. (mosl/lit) • Osmolarity is osmotcally active … This is estimated by measuring the volume of distribution of isotopes of water. According to "Nursing Standard," approximately 60 percent of the human body is water, and body water contains electrolytes. Body Fluid Compartments 2/3 (65%) of TBW is intracellular (ICF) 1/3 extracellular water 25 % interstitial fluid (ISF) 5- 8 % in plasma (IVF intravascular fluid) 1- 2 % in transcellular fluids – CSF, intraocular fluids, serous membranes, and in GI, respiratory and urinary tracts (third space) 11 2-Proteins → 18% of the body weight. Total body water (TBW) was 0.471±0.066 l/kg before haemodialysis and 0.466±0.054 l/kg after haemodialysis. It constitutes about 60 percent of the body weight. Fluid Compartments. The intracellular compartment is the area within the cell. Maximum rate of sweating is up to 50 mls/min or 2,000 mls/hr in the acclimatised adult. Slide 1 ; FLUID THERAPY ; Slide 2 ; Body Fluid Compartments : ICF:55%~75% Intravascular plasma X 50~70% lean body weight Extravascular Interstitial fluid TBW ECF 3/4 1/4 Male (55%) > female (45%) Most concentrated in skeletal muscle … Drug enters the body by absorption.Inside the body, drugs move in the blood to different parts of the body. Osmolarity is higher than serum osmolarity Hypotonic • A hypotonic solution shifts fluid out of the intravascular Iso-osmolar solutions which are not isotonic: 5% dextrose and intracellular fluid. Drugs that have relatively small Vd (e.g. Plasma and interstitial fluid are the major components of ECF. Total body water is 60% of body weight. Extracellular Fluid 3. Describe the composition of the major body fluid compartments. A balance between fluids and electrolytes is necessary if cells are to survive and function normally. Extracellular Fluid. While the water or fluids are moved in and out depending on need or activity, the body can also move the electrolytes. Intracellular fluid contains large quantities of potassium, magnesium, phosphates, sulphates and proteins. The human body is chiefly made of fluid. 2. Body Fluid Compartments 2/3 (65%) of TBW is intracellular (ICF) 1/3 extracellular water 25 % interstitial fluid (ISF) 5- 8 % in plasma (IVF intravascular fluid) 1- 2 % in transcellular fluids – CSF, intraocular fluids, serous membranes, and in GI, respiratory and urinary tracts (third space) 11 PHYSIOLOGIC DIFFERENCES. 2. Presentation Summary : Describe of body fluid compartments as intra-cellular fluid (ICF) Extra-cellular fluid (ECF), interstitial fluid, trans-cellular fluid and total body water.